Clenbuterol Steroids Reviews

By | February 29, 2016

What Is Clenbuterol?

Clenbuterol is known as a sympathomimetic amine, and it belongs to a class of drugs known as sympathomimetics. Other drugs in this classification include Caffeine, Albuterol, Ephedrine, and many others as it is a very broad category of drugs. All of these compounds (Caffeine, Albuterol, Ephedrine, Epinephrine, Norepinephrine, etc.) are very much ‘cousins’ of one another as they are all related with close similarities. The manner by which Clen works is by stimulating the sympathetic central nervous system in a variety of different pathways through different receptors known as adrenoreceptors that are located in all sorts of different tissues and cells in the body. Within the broad spectrum of the cells that these receptors are found in, Clenbuterol can act on these receptors and result in various different outcomes depending on which cell the receptors are found. The important thing to understand is that there are approximately 9 different adrenoreceptors found in the body, and are labeled as Alpha or Beta receptors with varying different numbers affixed to them (for example, Alpha-1, Alpha-2, Beta-1, Beta-2 receptors and so on and so forth). This is where the various different symathomimetic drugs differ from one another, in their receptor interaction. In Clenbuterol’s particular case, it is well known for targeting the Beta-2 receptors (effectively making Clenbuterol known as a B2 receptor agonist). The importance of this in regards to Clenbuterol’s fat burning advantages will be further explained later on. Clenbuterol has been shown to have a half-life of approximately 34 hours, making single daily doses a normal administering practice.

Common Uses for Clenbuterol

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Although Clen in athletic, modeling, show business, and bodybuilding circles is primarily utilized as a fat loss agent, it was actually never originally utilized for this purpose in medicine. Many sympathomimetic drugs have been classified for use in treating a broad variety of conditions. In particular, Clenbuterol is widely used in asthma medications for those suffering from asthma. It can be commonly found as a main active ingredient in asthma inhalers for this purpose. This stems from the fact that Clenbuterol, when activating Beta-2 receptors in various tissues, enables bronchial dilation (opening of the airways) in the lungs and airways through the nose and throat. This is actually a well-known aspect of all sympathomimetic compounds (to varying degrees), including the body’s own neurotransmitters/hormones Epinephrine and Norepinephrine (Adrenaline and Noradrenaline respectively), by which drugs such as Clenbuterol have many similarities and actions. Other conditions which sympathomimetic compounds such as Clenbuterol are used for include: hypertension, cardiovascular shock/slowdown, arrhythmias, migraine headaches, allergic reactions and swelling, histamine reactions, and anaphylactic shock. Although Clenb is a Beta-2 receptor agonist, it does have activity on other receptors in tissues, such as Beta-1 receptors for example, but this is to a very small extent. In comparison to Ephedrine, for example, Clenbuterol could be explained through the analogy that Clenbuterol’s action is akin to having several nails sticking out of a wooden surface where a hammer is used to hammer one specific nail on the head, but Ephedrine is the equivalent of using a larger sledgehammer to hit multiple nails on the head to drive them into the wood. Although not an exact analogy, this explains Clenbuterol’s activity fairly accurately.

Clenbuterol’s Activity In Tissues

The use for Clenbuterol as a bronchodilator for asthma patients has been previously outlined, as well as the other clinical applications. However, what has not been yet explained (and what our main concern is) is its effect on fat metabolism. It is also known that Clenbuterol itself holds very mild anabolic effects on muscle tissue as well. Various animal studies have demonstrated Clenbuterol’s ability to have an anabolic effect on muscle tissue, although extremely mild and minor. The various studies that have been done, as well as the decades of anecdotal evidence from human bodybuilder users, demonstrate that this anabolic effect is quite negligible although it does exist. It would then behoove a user of Clen to understand that the use of this compound for purely its ‘anabolic’ effects would likely end up with disappointing results. It is therefore more important to regard Clenbuterol as a thermogenic fat loss agent first and foremost, and to treat it in this manner rather than an ‘anabolic’ agent (of which it is very poor at doing so). Evidence for this has been found in analysis of the studies done on animals whereby the animals were administered doses of Clenbuterol that were far above what the average human user would use for a cycle. This raises the common question as to whether Clenbuterol is actually anabolic at all in humans. With this being said, the Beta-2 agonist trait of Clenbuterol lends it some quite strong fat loss attributes. Through stimulating Beta-2 receptors on fat cells, Clenbuterol directly activates fat metabolism and begin the process of breaking down triglycerides into free fatty acids. It is well known that Beta-2 receptors on fat tissue play a very large role in fat loss, more so than other Beta and Alpha receptors on fat tissue. It is for this reason also that cattle are frequently administered Clenbuterol alongside anabolic steroid compounds in order to have the leanest possible beef or pork for slaughter and consumed as food. However, it is important for any potential user to understand that Clenbuterol may not result in effective fat loss for everyone. Some may be better responders in terms of fat metabolism from a compound such as Ephedrine (due to its better interaction with multiple receptor types) than with Clenbuterol. With that being said, it is well known that Clenbuterol should affect most people with significant fat loss effects – but non-responders (or poor responders) do exist.

Finally, one extremely important consequence to consider when it comes to Clen is the issue of Beta-2 receptor downregulation. Through prolonged daily use, Beta-2 receptors down regulate in response to the receptor stimulation from Clenbuterol itself. This results in a diminished fat loss effect that must be remedied by either time off from the drug, or the use of Ketotifen. The diminished fat loss for most people seems to be reported to be around the 2nd week mark, whereby a 2 week break is the normal protocol in order to have receptor sites naturally up regulate themselves.

Clenbuterol Side Effects

Clenbuterol side effects are very similar to that of any other sympathomimetic compounds. All sympathomimetic compounds (such as Caffeine, Albuterol, Ephedrine, Epinephrine, Norepinephrine, etc.) carry more or less the exact same side effects. The difference between any of the listed sympathomimetic compounds (and the countless others that exist in the world) is the level of severity of the various side effects associated with each compound. Various sympathomimetic type side effects may also be less pronounced with a particular compound in comparison with another, and although one particular side effect may be less prominent, another side effect may be harsher than the compared compound. For example, many users who have used Ephedrine and Clenbuterol (at separate times, of course) have claimed to experienced more pronounced side effects in one particular area of one drug over the other – however, the overall general side effects associated with sympathomimetic stimulants more or less remains existent with both compounds. With this being said, Clen carries the same side effects as that of other central nervous system (CNS) sympathomimetic stimulants which includes fairly common key physical side effects: tremors (shaky hands), insomnia, sweating, headaches, heightened blood pressure, and nausea. CNS stimulants such as Clenbuterol also carry with them the potential for a select few common psychological side effects which are not commonly mentioned. These include: anxiety, heightened euphoric sensation (improved mood), and depression (resulting from a possible crash following use). Less common or rare side effects (mostly associated with overdoses) include: tachycardia (rapid heart rate), irregular heart rate, rapid breathing, severe nausea, vomiting, and diarrhea. Clenbuterol is not an anabolic steroid and therefore does not carry with it any potential virilization or gender-altering type side effects. A particular side effect that is associated with Clenbuterol and not with many other CNS stimulants (with the exception of Albuterol) is that of muscle cramps.

Clenbuterol Cycles

It is well known that Clenbuterol use results in rapid down-regulation of beta 2 receptors. This is due to the powerful stimulatory effect of the drug. It is therefore pointless to use clen for long periods without a break. Some believe that a two day on, two day off dosing schedule will allow adequate potential for receptor up-regulation.

Users who wish to partake in Clenbuterol cycles where Clenbuterol is stacked alongside anabolic steroids usually stack with a select few anabolic steroids that are best known for being ‘cutting agents’. This implies that the anabolic steroids are compounds that do not promote water retention, fat gain due to Estrogenic side effects, and promote a general overall lean hardness to the physique. Some of the most common anabolic steroids that are known to be stacked in Clenbuterol cycles are: Trenbolone, Winstrol, Masteron, Anavar, Turinabol, Primobolan, and of course the base of any of these cycles – Testosterone. The following are some samples of how Clenbuterol would commonly be stacked in a cutting cycle.Please note that in all of the following listed sample cycles, it is assumed that the user will have slowly ramped up their Clenbuterol dose to the peak doses listed.

Sample Clenbuterol Cycle (12 weeks total cycle time)

Weeks 1-12:
– Testosterone Enanthate at 300mg/week
– Trenbolone Enanthate at 400mg/week

Weeks 1-8:
– Clenbuterol at 120mcg/day
– Ketotifen every second week of Clenbuterol use at 2mg/day

This sample cycle is a fairly basic cycle, outlined with the idea of using Ketotifen to maintain Beta-2 receptor up regulation. This grants the user the ability to run Clenbuterol consistently for 8 weeks straight without the need to halt and then re-initiate use after break periods. Testosterone and Trenbolone are utilized as the anabolic steroids in this cycle, with Trenbolone notably being very beneficial for its very strong nutrient partitioning effects. This grants further fat loss on cycle.

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