Clenbuterol Slimming Pills (Size Zero Pill)
The weight loss that results with Clenbuterol can be quite significant in many users; women and men. It is important to keep in mind that there are those who will not respond as well to Clenbuterol in terms of fat loss compared to others. This can be due to a great variety of factors, but one main factor of which is genetics and individual response. As we all should know and understand, every person’s body is different, and every person’s body will react in some different way to any one given substance. With that being said, the fat loss resulting from Clenbuterol use is quite well documented in both clinical studies as well as anecdotally.
A quick re-cap of the general method by which Clenbuterol works (ex; astralean clenbuterol 40 mcg, oxyflux clenbuterol .02 mg, clenbuterol sopharma 0 02 mg, clenbuterol spiropent) : Clenbuterol is known as a Beta-2 selective sympathomimetic amine. This means that Clenbuterol binds to and acts on Beta-2 adrenergic receptors in the body. Although Clenbuterol does have activity on other receptors, its primary interaction is with that of Beta-2 receptors. These receptors can be found in all types of different cells across the human body. In the specific case of fat cells, Beta-2 receptors when activated signal the process of lipolysis (fat breakdown) to the fat cell. As a result, fat loss can be greatly enhanced with Clenbuterol in combination with a solid nutritional regimen (preferably a caloric deficit to promote even greater fat loss) and a proper training regimen.
The clinical studies performed on the fat loss and body composition effects of Clenbuterol are almost exclusively done on animals. This is why it is strongly debated as to whether or not Clenbuterol is truly ‘anabolic’ in humans versus animals. However, the fat loss effects have been well documented in both humans as well as animals. In one particular study done on rabbits in 1996, 20 rabbits were administered 100 micrograms per day of Clenbuterol versus a control group of 20 additional rabbits. The results indicated that in the rabbits that were administered Clenbuterol vs. the control group, perirenal and interscapular fat percentages in the carcass were reduced (3.23 vs 3.83 and 0.68 vs 0.86, respectively) 1. Most studies performed on animals have been performed on rabbits, rats, mice, and pigs with all results generally having the same outcome. It is because of this that Clenbuterol at one time was utilized to improve feed efficiency and lean meat product in cattle. However, it has been illegal since 1991 in the United States for farmers to utilize Clenbuterol on cattle as well as the European Union since 1996. It is legal, however, for Clenbuterol to be used on animals that are deemed as non-food producing animals.
An important fact for any person considering the use of Clenbuterol for weight loss to understand is that Clenbuterol may initiate lipolysis, but it does not initiate adipose apoptosis (fat cell death). It was strongly hypothesized that Clenbuterol indeed did initiate apoptosis of fat cells. However, in one particular study on mice it was found that direct stimulation of Beta-2 receptors by Clenbuterol does not cause apoptosis in adipocytes, despite a direct lipolytic stimulation and attenuation of adipogenesis. 2 What this means is that Clenbuterol did initiate lipolysis and slow down and/or halt the storage of more fat, but it was not confirmed that Clenbuterol has the ability to cause fat cell death. In an ideal world, we would all hope to stimulate fat cell apoptosis but what occurs with Clenbuterol-related fat loss as well as fat loss in general by normal means is simply a loss of fat that is stored within fat cell ‘sacks’. Simply put, these ‘sacs’ which are the cells shrink in size – but the cells still remain. The number of these fat cells in any given person’s body is determined by the individual’s genetics and how many fat cells the person is ‘programmed’ to have grown in their youth. This number of cells remains with the person throughout their life. The only currently known method by which one is able to remove the actual cells themselves is that of mechanical means such as liposuction or various other mechanical or radiological methods.
The typical fat loss that is reported anecdotally by people ranges anywhere from an additional 1-4 lbs. of fat per week. Once again, the numbers reported are largely dependent on each individual and their response as well as other factors such as nutritional habits, training methods, and so on and so forth. Of course, the addition of potentiators such as Ketotifen Fumarate also has potent effects on the fat burning ability of Beta-2 agonists such as Clenbuterol or Albuterol. An individual in a hypocaloric (caloric deficit) state who trains on a regular basis can expect to see far more fat loss per week than an individual in a hypercaloric (caloric surplus) state that does not engage in physical training. Similarly, an individual who is in a hypocaloric state who stacks a cycle of anabolic steroids and thyroid hormones with Clenbuterol in comparison with an individual in a hypocaloric state will not only lose dramatic amounts of body fat per week in comparison with the person who does not, but the former individual will also likely retain far more lean mass and possibly even add additional muscle mass in the process. Again, there are an almost infinite number of factors that determine the rate by which fat loss is increased by Clenbuterol and this is why there is no exact definite answer for the most common question: “How much fat loss can I expect from a Clenbuterol cycle at X dose for X length?”. These questions are frequent, yet there is no exact answer. The closest ballpark figure that can be given is that of an additional 1-4 lbs. of fat per week, dependent on a plethora of different adjusting factors.
1 Effect of clenbuterol on productive performance, body composition and muscle biochemistry in the rabbit. Hulot F, Ouhayoun J, Manoucheri M. Institut National de la Recherche Agronomique, Centre de Toulouse BP 27, 31326 Castanet, Tolosan Cedex, France.
2 Effect of clenbuterol on apoptosis, adipogenesis, and lipolysis in adipocytes. J Physiol Biochem. 2010 Sep;66(3):197-203. Epub 2010 Jun 10. Kim HK, Della-Fera MA, Hausman DB, Baile CA. Department of Food Science and Nutrition, The Catholic University of Korea, Bucheon, South Korea.